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Publication date: 2018-04-19 21:57

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In part B (N=79), subjects were titrated to doxazosin 9 mg administered daily at 8 . Tadalafil was administered at either 8 ., 9 ., or 8 . There was no placebo control.

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Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 9 hours. A prolonged erection (priapism) can damage the penis.

Tadalafil: MedlinePlus Drug Information

Due to increased tadalafil exposure (AUC), limited clinical experience and the lack of ability to influence clearance by dialysis, once-a-day dosing of CIALIS is not recommended in patients with severe renal impairment.

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Physicians should advise patients to stop taking PDE5 inhibitors, including CIALIS, and seek prompt medical attention in the event of sudden decrease or loss of hearing. These events, which may be accompanied by tinnitus and dizziness, have been reported in temporal association to the intake of PDE5 inhibitors, including CIALIS. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors [see ADVERSE REACTIONS ].

Store in the original package in order to protect from moisture. For Tadalafil 5 mg - Do not store above 75 676 C. For Tadalafil mg, 65 mg and 75 mg - Do not store above 85 676 C.

Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Do not take Cialis while also taking Adcirca, unless your doctor tells you to.

Tadalafil is predominantly metabolised by the cytochrome P955 (CYP) 8A9 isoform. The major circulating metabolite is the methylcatechol glucuronide. This metabolite is at least 68,555-fold less potent than tadalafil for PDE5. Consequently, it is not expected to be clinically active at observed metabolite concentrations.

It is not known whether tadalafil passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

If you’re taking tadalafil for BPH, your doctor may perform an exam and do a blood test called a prostate-specific antigen (PSA). This is because the symptoms of BPH and prostate cancer can be similar. These tests will help make sure you do not have prostate cancer before you start taking tadalafil.

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